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What is leaky gut syndrome and its symptoms?

All diseases begin in the intestines”, a common saying of Hippocrates, the father of modern medicine, and this saying has been proven true more than two thousand years after his death, and leaky gut syndrome or “increased intestinal permeability” is one of the diseases that greatly affects your health, in this report we learn about Leaky gut syndrome and its symptoms, according to “draxe”. What happens when you have a leaky gut? The intestine is protected by a single layer of specialized epithelial cells that are linked together by tight junction (TJ) proteins. As one study shows, the Symptoms of leaky gut are the result of an abnormality in the function of the intestinal TJ.


These proteins are the gateway between the intestines and the bloodstream. They control what is allowed to pass into the bloodstream from the digestive tract. More than 40 different TJ proteins have been identified to play a role in gut health.




TJ proteins have a very delicate job that must maintain the delicate balance between allowing vital nutrients to enter the bloodstream, while remaining small enough to prevent xenobiotics (pathogenic substances such as toxins and bacteria) from exiting the digestive tract into the rest of the body.


What are the symptoms of leaky gut?


Some of the most notable signs that you may have this disease include:




-Joint pain


Infectious diarrhea


Irritable bowel syndrome


Inflammatory bowel diseases (ulcerative colitis, Crohn’s)


Overgrowth of bacteria in the small intestine


Celiac disease


Cancer of the esophagus, colon and rectum




Respiratory infections


Acute inflammatory conditions (sepsis, multi-organ failure)


Chronic inflammatory conditions (such as arthritis)


Thyroid disorders


Obesity-related metabolic diseases (fatty liver, type 2 diabetes, heart disease)


Autoimmune diseases (such as lupus, multiple sclerosis, type 1 diabetes, Hashimoto’s, and more)


Parkinson’s disease


Chronic fatigue syndrome


Tendency to be overweight or obese


Leaky gut may not directly cause any of these conditions – in fact, people with gut problems are more likely to develop a number of other health issues.


What is the treatment for leaky gut?


Several tests for leaky gut syndrome are available that can help confirm the diagnosis and point you in the direction of correct treatment. Tests are useful for identifying specific sensitivities and detecting the types of toxins or deficiencies that are contributing to your symptoms.

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