Why are some people naturally less resistant to Covid-19?
A team of researchers affiliated with a group of institutions in the United Kingdom and Brazil has partly solved the mystery of why some people are naturally less resistant to Covid-19 than others.
A new study shows that small differences in an individual’s genetic makeup may help explain why some people build a strong natural defense against Covid infection, while others become severely ill.
Researchers at the University of Glasgow’s Center for Virus Research have identified a specific protein called OAS1, which is believed to play a key role in shaping the early stages of an individual’s response to Sars-CoV-2.
When a human cell is infected, the OAS1 protein interacts with interferon signaling by calling for an immune response when the SARS-CoV-2 virus is detected, allowing the cell to begin attacking the virus’s genetic material.
Previous studies have also shown that these signals can prevent the replication of the SARS-CoV-2 virus.
The study, published in the journal Science, suggests that some people express a more protective version of OAS1 that binds to membranes using a prenyl group as part of the signaling process, which is the addition of a single fat molecule to the protein encoded by the OAS1 gene.
Because coronaviruses hide inside cells and replicate their genomes inside vesicles made of lipids, pre-OAS1 is better suited to seek out Sars-CoV-2 and direct cellular weapons to attack it.
The researchers looked at the transcriptomes of 500 Covid-19 patients who experienced a wide range of symptoms, and found that those who had not been exposed to prior OAS1 experienced more severe symptoms. Why some people are born without this enzyme is still a mystery, but the team’s work could help lead to new types of vaccines against Covid-19 and other types of infections.
Based on their findings, the researchers turned their attention to another mammal, the horseshoe bat, one of the presumed sources of SARS-CoV-2, and found that it did not possess the OAS1 preform that protects humans from the virus. This discovery could help explain why bats are such prolific hosts for a variety of viruses.
This means that the virus never needed to adapt to evade this line of defense, but if the SARS-CoV-2 virus mutates and gains the ability to circumvent the defenses generated by OAS1 protein promerization, the virus could potentially become more virulent or transmissible.
Trapped viruses within a new strategy for the vaccine industry
Trapped viruses within a new strategy for the vaccine industry
Chinese scientists create a vaccine that contains the live virus in a protective water gel in order to activate the body’s immune response quickly, safely and effectively without side effects and safety problems.
Promising technology for health protection
BEIJING – Chinese scientists have devised a new strategy for making vaccines that avoids the disadvantages and side effects of inactivated virus technology.
Inactivated vaccines contain a killed form of the pathogen, to help the immune system trigger a response without causing disease.
The manufacture of vaccines with a whole virus raises concerns about reducing immunity and raises questions about safety.
This method also requires time-consuming production processes, which hinders its widespread application.
Recently, the risks of new viral outbreaks have led to an urgent need for safe and effective ready-to-use vaccines.
The strategy involves trapping the live virus in a protective hydrogel in order to quickly, safely, and effectively activate the body’s immune response.
Researchers from Zhejiang University and the Beijing Institute of Biotechnology demonstrated an experimental vaccine consisting of live, wild-type Zika virus, a mosquito-borne single-stranded RNA virus, Xinhua reported.
They prevent the escape of viral particles via electrostatic interaction but allow the passage of immune cells
The researchers trapped the virus in a water gel using chitosan scaffolds, which can prevent the escape of viral particles through electrostatic interaction but allow the passage of immune cells.
The vaccine, injected under the skin of mice, was shown to activate normal immune responses, resulting in effective humoral and cellular immunity, thus protecting the rodents against deadly Zika infection, according to the study, which was published in the latest issue of the journal Nature Biomedical Engineering.
This study shows that virulent virus strains can be directly converted into vaccines by engineering virus-trapping microenvironments.
The study represents a promising strategy for protecting health against emerging infectious diseases, the researchers said.
Which type of respirator offers the best protection against Omicron?
Which type of respirator offers the best protection against Omicron? And does Omicron affect the intestines? Did millions die from the “Covid-19” vaccine? Do “Covid-19” vaccines reduce the effectiveness of the immune system? How do you keep yourself safe when riding in a car and protect yourself from Corona? The answers are in this comprehensive report.
Which type of respirator offers the best protection against Omicron?
Medical Corporation in Qatar said that masks play an important role in combating “Covid-19” infection, including the Omicron mutant if used appropriately.
The Foundation recommended, regarding the use of masks to protect against Omicron, the following:
Respirators recommended for use by the general public to protect against Omicron
To obtain the best results, a medical mask should be placed, because it is better than a cloth mask in preventing infection, so that it is:
3 layers of good protection against external particles.
Underwire at the nose to allow the mask to be fixed without air escaping from the sides.
Masks recommended to be used for protection from Omicron for people at high risk of severe “Covid-19” infection
People who are prone to severe illnesses, such as the elderly and those with chronic illnesses, should wear an N95 mask when going out or close to others.
These masks contain multiple layers of synthetic materials that provide a high level of protection against particles outside.
Fallacies about “Covid-19” and its vaccines
Here we present a set of inaccuracies refuted in detail by the World Health Organization with comprehensive infographics on the subject.
Do Covid-19 vaccines reduce the effectiveness of the immune system?
No, on the contrary, “Covid-19” vaccines actually improve the efficiency of our immune system, and help it respond to the virus when it enters the body. Vaccines help our bodies according to the World Health Organization
Did millions die from the “Covid-19” vaccine?
No. Death due to symptoms resulting from receiving the “Covid-19” vaccine is very rare. Millions have died due to severe illness and health complications related to “Covid-19.” Since it began spreading until today, “Covid-19” has killed more than 5 million people.
“Covid-19” vaccines with messenger RNA (mRNA) technology
They are vaccines that make our cells create a harmless protein similar to the protein in the “Covid-19” virus, so that our immune system gets used to it, and enables it to protect us better when infected with the real virus.
If I have received the COVID-19 vaccine, can I donate blood and organs?
Yes, you can donate blood or organs. Many people who have undergone organ transplants have received the vaccine and have not had any complications.
Do Covid-19 vaccines affect breastfeeding?
If you’re breast-feeding, get vaccinated. The vaccine will help your body make antibodies and reduce your risk of getting too sick to care for your baby.
Do “Covid-19” vaccines have severe effects on the body’s organs?
No, “Covid-19” vaccines do not have any negative effect on the body’s organs.
How do you keep yourself safe and protect yourself from corona when riding a car?
The world health Organization advice to following to prevent infection or death due to “Covid-19”:
Take the vaccine.
Keep a safe distance.
Put on the mask.
Open the windows.
Clean your hands.
Cover your mouth with your elbow when coughing or sneezing.
Medical advice for dealing with Omicron
The world is suffering from a rapid spread of the Corona virus through its new mutant, Omicron, which prompted the World Health Organization to talk about the “tsunami” of the disease spreading across the world, with record numbers of injuries recorded.
Family doctor Rami Eyupoglu gave, via Anadolu Agency, a set of medical advice on ways to confront the rapid spread of the Omikron virus.
Eyupoglu said, “One of the most important information about the Omicron mutant is that it has undergone many changes, and it is an unusual combination of mutations, and the most important thing is that 83% of the infected have a cough, 87% of the infected have nasal secretions or congestion, and 74% of the infected have fatigue and tiredness.” .
“The mutant Omicron has mild symptoms that are concentrated in the upper respiratory tract and has no symptoms in the lungs,” he added.
And he indicated that “it spreads rapidly, infecting many people with the disease at the same time, and this leads to fatigue of the workforce in hospitals, so everyone must take the necessary measures to deal with Omicron.”
Here are the measures that Dr. Eyupoglu called for taking to deal with Omicron:
Continue to wear masks and maintain social distancing, especially in crowded places, and it is best to avoid those places, as well as closed places, and in homes, rooms must be ventilated for 10 minutes every two hours.
Get the booster dose of the corona vaccine, and this dose will help to some extent protect against Omicron, and when you get the dose, the percentage of the level of antibodies will rise much higher than it was at its peak with the second dose.
Continue to get the Corona vaccine.
The demand for corona tests at the slightest suspicion of infection with “Covid 19” disease, and tests and detection swabs must be carried out.
Home isolation, the infected person has to isolate himself from the rest of his family, especially at the present time due to the rapid spread of Omicron, and according to our follow-up to the disease, the infections are constantly increasing, but there are no increases in clinical cases or in the number of deaths.
I advise everyone to maintain the strength of the physical immunity by eating foods and drinks that increase the body’s immunity, especially citrus fruits, broccoli, garlic, ginger and green tea.
Stay away from sadness and nervousness because a good psychological state and happiness increases immunity.
Maintain oral hygiene by brushing the teeth at least twice a day, and rinsing continuously with warm water, because according to the results so far for the Omicron mutant, it is highly concentrated in the upper part of the respiratory system.
I advise everyone to take vitamin D, because we are not exposed to the sun in the winter, and it is one of the most important elements in strengthening the body’s immunity.
Does Omicron affect the intestines?
The “Covid-19” virus causes complications in the respiratory system, but it seems that the new strain affects the digestive system as well!
In this report, published by the Indian “Healthshots “ website, author Parmita Yunal says that symptoms such as vomiting, nausea, and feeling abdominal pain without fever may be evidence of Omicron infection. It is recommended to take a “Covid-19” test if these abdominal pains appear even without symptoms of shortness of breath or fever.
Omicron can affect the intestines regardless of the damage it may do to the upper respiratory tract.
Symptoms such as abdominal pain have become common in people infected with this new mutated strain, and even in people who have been vaccinated, and some include nausea, abdominal pain, vomiting, loss of appetite and diarrhea.
According to Dr. Manoj Goel, Director of the Division of Chest Diseases at Fortis Healthcare, “People may initially develop abdominal symptoms without feeling any respiratory concern, and may also complain of back and abdominal pain, nausea, vomiting, loss of appetite and diarrhea. It is likely that the cause It is an omicron injury to the intestinal mucosa and causing inflammation.
Dr. Manoj Goel confirms that people who have received two doses of vaccination complain of abdominal problems, but these symptoms are not serious and are not a major concern.
“Abdominal pain, nausea and loss of appetite should not be treated as normal flu symptoms. If you develop these symptoms, isolate yourself, avoid self-medication without consulting your doctor, and try to keep yourself well hydrated by drinking water, and eating regular, healthy and light meals including nuts.”
Dr. Manoj Goel stresses, “The need to take a Covid-19 test if you suffer from abdominal pain even if you do not have symptoms of shortness of breath or fever, because you may have Omicron.”
To relieve symptoms such as nausea and vomiting if Omicron is confirmed, Dr. Manoj Goel advises:
Eat cooked food.
Keeping hands clean.
Avoid sharing meals with others.
Avoid eating out.
Even if you do get vaccinated, be sure to follow all COVID-19 safety protocols.
The author cautions that the mutated strain Omicron is spreading rapidly. Scientists around the world are conducting studies to further understand this variant, which is likely to become dominant soon.
It has been found that the degree of infection of Omicron is more than delta, and it mostly causes mild symptoms, but also affects people who have previously been infected with the “Covid-19” virus or have even been vaccinated twice.
According to experts, Omicron’s symptoms are similar to those of the common flu and affect the upper respiratory tract. Coughing, fatigue, congestion, and a runny nose are some of the common symptoms associated with Omicron.
The scientists also noted that loss of smell and taste is less common among people who have recently tested positive for this strain
Protect yourself from Corona and its variants and strengthen your immune system with these tips
Therefore, the report, published on the “ healthline ” website, confirms that eating healthy contributes greatly to reducing the chances of infection with the virus and its variables, and protects you from many diseases because you have kept strengthening your immune system.
The report presented some prohibited foods, because they increase the chances of weakening the immune system, including:
Foods high in salt.
On the other hand, the report advised people to eat healthy foods rich in distinctive vitamins whose role is to strengthen the immune system, such as antioxidants, vitamins D, C and A, and zinc. To get these elements, you can eat more vegetables, fruits, nuts and legumes.
The report also pointed out the importance of eating fiber-rich foods because they have a significant role in strengthening the immune system, reducing exposure to any health complications, and also strengthening the immune system.
Finally, the report emphasized the role of a healthy diet rich in vitamins and distinct and important nutrients for the body in strengthening the immune system and reducing exposure to the resulting health complications.
Omicron spreads very quickly but is less dangerous
The omicron mutant would affect the lungs less than other corona mutant , according to “Fam Actoyal”. What is stated in the latest studies on this topic?
As the Omicron mutant continues to advance, new studies indicate its danger. And a new study has just revealed that it may be less dangerous to the lungs than other mutants.
According to the first available data, the omicron mutant is more contagious but causes less severe forms of Covid-19. An English-language study, published on December 28, 2021 on the BioRXiv platform, shows that the mutant discovered in South Africa appears to be less harmful than others, especially to the lungs.
Mutant omicron affects the lungs less
To achieve this result, the scientists infected mice with several Covid-19 mutants, such as Delta or Omicron. The first results are clear: rodents contaminated with the South African species display a “lower respiratory viral load”.
So Omicron will be less harmful to the lungs than other types of Covid-19. “We have some studies showing that this variant multiplies a lot in the cells of the nose, not in the back of the body, the bronchi,” Sylvie Brian, director of the Epidemiological Risk Management Department at the World Health Organization (WHO) confirmed to France Info.
Omicron is a “less virulent” type that spreads very quickly
According to her, this could explain why Omicron appears to be “less virulent” than other mutant. The English study also tends to this conclusion: mice contaminated with omicron actually show “less severe clinical signs” than those infected with other mutants.
So it appears that Omicron causes less severe forms of Covid-19. Two studies, one Scottish and one British, indicated that this mutation was associated with a “two-thirds reduction in the risk of hospitalization”. However, all of these findings should be taken with caution.
Sylvie Brian explains that Omicron is spreading very quickly According to data from Public Health France, more than 62% of positive Covid-19 tests showed a “profile compatible with the Omicron mutant” at the beginning of week 52 (from December 27, 2021 to 2 January 2022). Although it appears to cause some serious forms, the omicron mutant is considered dangerous, so health care professionals insist it’s important to receive a vaccine to protect against it.
All the information you need to know about the Corona virus
Middle East respiratory syndrome coronavirus (MERS-CoV) is a viral respiratory disease caused by one of the coronaviruses that was first discovered in Saudi Arabia in 2012. This type of virus represents a large family of viruses that can cause diseases in humans, the spectrum of which extends from the common cold to the syndrome Severe acute respiratory syndrome (SARS).
Corona virus symptoms
Symptoms of MERS include fever and cough or shortness of breath.
Pneumonia is also common, although it has been reported that some people with the infection are asymptomatic.
Gastrointestinal symptoms including diarrhea have also been reported.
Severe cases may include respiratory failure requiring artificial respiration and support in an intensive care unit.
And some patients had failure in the functions of some organs, especially kidney failure or septic shock.
The virus appears to cause more severe disease in people with weakened immune systems, the elderly, and people with chronic diseases, such as diabetes, cancer and chronic lung disease.
The mortality rate for people infected with MERS-CoV is around 35%, however this estimate may be an exaggeration, given that existing surveillance systems may not record mild cases.
Is there a vaccine against corona virus and what is the treatment?
There is currently no vaccine or specific treatment for MERS.
The treatment available is supportive and depends on the patient’s clinical condition.
How do people get infected with the respiratory corona virus?
The MERS virus is transmitted primarily from animal to human, but it can also be transmitted from person to person.
From animal to human
Corona virus is a zoonotic virus, that is, it is transmitted between animals and humans.
Scientific evidence indicates that people contract the infection through direct or indirect contact with Arabian camels.
The MERS virus has been detected in Arabian camels in a number of countries, including Egypt, Oman, Qatar and Saudi Arabia.
There is other data indicating that the Corona virus is widespread in Arab camels in the Middle East, Africa and South Asia.
It is possible that there are other animal reservoirs, but animals such as goats, cows, sheep, buffaloes, pigs and wild birds have been tested and have not detected the virus.
The Middle East Respiratory Syndrome virus is not easily transmitted between people, except in the case of close contact
Such as if clinical care is provided to an infected patient without strict hygiene measures.
The transmission of the disease between persons has been limited to this day, and it has been detected among family members, patients, and health care workers.
Most MERS cases reported to date have occurred in healthcare settings.
Detection of people infected with the Corona virus
It is not always possible to detect people infected with MERS virus because the early symptoms of this disease are non-specific.
For this reason, all health care facilities should implement standard infection prevention and control practices.
It is also important to investigate the travel history of people with respiratory infections to determine whether they have recently visited countries where the coronavirus is actively circulating or have been in contact with Arabian camels.
What do you do if you come into contact with someone with corona syndrome?
If you have been in close contact with a person infected with MERS-CoV in the last 14 days without taking the recommended infection control precautions, you should contact a health care provider to assess your condition.
Nutrition tips against corona virus
- Consumption of animal products including dairy and meat, raw or undercooked, carries a severe risk of infection caused by a range of organisms.
- Appropriately prepared animal products, by cooking or pasteurization, are safe to consume but should be handled carefully to avoid cross-contamination from uncooked foods.
- Camel meat and milk are nutritious products that can be consumed after being pasteurized, cooked or treated with any other heat treatment.
- Until more is understood about the coronavirus, people with diabetes, kidney failure, chronic lung disease, and immunocompromised individuals will be considered to be at high risk of severe illness from infection with the coronavirus.
- Therefore, this group of people, especially in the Middle East, should avoid contact with Arabian camels and should avoid consuming their raw milk or urine or eating their undercooked meat.
- People should avoid direct contact with any animal confirmed to be infected with the Coronavirus